I'm running Zephyroth's 10.5.2 Rev1 on an AMD X2.
So far everything had been working very nicely and all problems could be solved with some searching.

One problem that I couldn't directly find a solution for where Toast 9 and Popcorn 3 crashing on launch with this error:

Exception Type: EXC_BAD_ACCESS (SIGSEGV)
Exception Codes: KERN_INVALID_ADDRESS at 0x00000000b5b5b5b5
Crashed Thread: Unknown

I found this thread for WoW that crashed witht the same error message:
http://osx.kbot.de/comments.php?DiscussionID=616

I downloaded Marvin's AMD Utility from here:
http://forum.insanelymac.com/index.php?showtopic=67917

and first tried to run it on the Toast application to no avail. Then I ran it on /System/Library/Frameworks and it found three cpuids the OpenGL framwork.

I was able to fix the startup crash by creating a patcher package with Marvin's Utility and then applying the patch as super user (I didn't have to restart into single user mode) like this:

- sudo -i
(enter your password)
- cd ~/Desktop/2008.03.23_at_19.39/patches
(or where ever your patch is)
- ./patcher cpuid.txt
- exit

I didn't even have to reboot, Toast and Popcorn launched fine after that. Though I haven't tried to do anything with those applications yet.

Hope this info is useful to some!